The responsibility of regulating the medical usage of ionizing radiation is disseminated among several authorities such as the National Regulatory Council (NRC), federal states, and regional government organizations. The NRC is charged with the mandate of controlling the possession and use of byproduct and source radioactive substances in the medical field. Byproduct material is useful in processes such as calibration of equipment, manufacture of radioactive drugs, analysis of bone minerals, and gadgets that carry out fluorescence imaging and brachytherapy (NRC par. 1).

Source material, on the other hand, is utilized in radiation protection and designing of equalizers in some gadgets. In addition, certain models of pacemakers are run by cells that contain nuclear substances. Therefore, the NRC provides special licenses to authorize the use of byproducts for purposes other than the administration of carbon-14 containing capsules during in vivo diagnostics. This license applies to four categories of byproduct materials as stipulated by 10 CFR Part 35. The four categories are diagnostic medical use, therapeutic medical use, medical research, and in vitro diagnostic tools.

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In medical diagnostic use, the usage of byproduct radioactive material is indicated in radioactive uptake, strength, secretion, imaging, or diagnosis of conditions at localized positions in medical or research processes. The associations of radiolabeled medications with bodily processes help in getting medical data. In such procedures, it is required that sealed sources provide the radiations necessary for the imaging procedures, which may be aimed at establishing tissue density. The use of portable imaging gadgets in dentists and podiatry also falls under this category.